News Stories

Why the Insect Cell System is a Boost for Vaccine Development

In an article published by New Scientist this week as part of the Value of Vaccines campaign, Prof. Linda King, founder of Oxford Expression Technologies explains why the insect cell system has become a popular platform for vaccine development – particularly in the light of the Covid-19 pandemic. FULL ARTICLE

SARS-CoV-2 (COVID-19 Virus) Research

OET is currently helping COVID-19 research efforts by producing the recombinant spike glycoprotein of SARS-CoV-2 for clients. The protein will be used for further research, diagnostics and potential vaccine production. OET is also engaged in in-house COVID-19 research and is working on an insect cell-based vaccine using our flashBAC system enabled through funding from Innovate UK/Department of Health through the Vaccines for Global Epidemics:development and manufacture initiative

Message to Customers

At the present time Oxford Expression Technologies remains open and is working to complete client projects and dispatch kits and products. Our timescales may be slightly delayed whilst we comply with Government restrictions and prioritise the safety and wellbeing of OET staff. We will be contacting customers to ascertain that they are able to receive goods before shipping and are pleased to report that we can now ship media to

Introduction to the Baculovirus Expression System

Baculoviruses are in many respects an odd choice for use as an expression system to make recombinant proteins.  In their natural environment they infect insect larvae/caterpillars, which frequently results in the death of the host and its reduction to a puddle of progeny virus (Fig. 1).  They are also unusual in that they produce two structurally different forms in their life cycle. The first is a lipoprotein-enveloped particle that buds

Selecting a Protein Expression System

A major decision facing anyone starting a new project requiring any quantity of recombinant protein is selecting a protein expression system. A quick search online will unearth a large number of options and an often bewildering choice of different vectors to use within any given system. For the novice, this can be daunting! It may sound obvious, but the first thing to do is to decide what you want your