News & Press

OET Presenting at South Wilts Virus Group Annual Meeting

OET will be sponsoring and presenting at this year’s South Wilts Virus Group (SWVG) annual meeting on Thursday 24th May. The event, hosted by Oxford Brookes University Department of Biological and Medical Sciences, will allow OET scientists to exhibit our current research achievements and network with other specialists in the virology field. The SWVG is a forum for virologists in the Wiltshire/Surrey/Berkshire/ Oxfordshire region. The organisation originally began in 1952

OET is Awarded £2 Million Vaccine Development Contract

Oxford, UK – 4th May 2018   Oxford Expression Technologies Ltd (OET) is pleased to announce that it has been awarded a £2M contract from Innovate UK as part of the ‘Vaccines for Global Epidemics’ Round 2 competition. The award will allow OET to continue its ongoing work in developing the first economically viable vaccine against Crimean Congo Haemorrhagic Fever (CCHF) virus. The Vaccines for Global Epidemics competition supports the

Storing Cells at -80°C?

Every so often we are asked if storing insect cells at -80°C is a viable option if you haven’t got access to liquid nitrogen cryogenic facilities.  Our standard response is that this is not a good idea for long term storage of viable cells.  This is largely based on historical dogma that says that cells do not preserve their viability for long at these temperatures.  However, since one of our

Product Launch – pOET8!

November marks the welcome of OET’s newest product – the pOET8 baculovirus transfer vectors (pOET8.VE1; pOET8.VE2; pOET8.VE3).  Compatible with any baculovirus expression system, including our own flashBACTM technology, the new range of pOET8 vectors are proven to help increase recombinant protein production in insect cells. The increased yield is achieved by allowing co-expression of foreign genes with a vankyrin expression cassette.  This gene cassette comprises the Campoletis sonorensis ichnovirus P-vank-1 protein

baculoQUANT Titration of Recombinant Baculoviruses

There are many methods available for the titration of recombinant baculoviruses.  One of the most convenient is the use of the quantitative polymerase chain reaction (QPCR), which assesses how much virus DNA is present in a freshly-amplified stock.  This is compared with a standard curve derived from a control virus stock to give an infectious titre expressed as Q plaque forming units (pfu) per millilitre.  OET Ltd market the baculoQUANT™

flashBAC 5+1 offer

OET’s flashBAC 5 reaction kit ranges are some of our most popular products. However, recent feedback has revealed that some customers are reluctant to make use of the positive control transfer vector as this sacrifices 1 reaction and so reduces the number of their own viruses that they can produce. In recognition of this issue, until further notice, we are increasing the amount of flashBAC DNA in all of our

OET at ISBioTech Washington 6-8th March

OET founders, Linda King and Bob Possee will be attending ISBioTech in Washington, 6-8th March 2017.  Linda will be presenting a talk entitled, “BacMam Expression Vectors: Applications in Gene Therapy”.  The use of BacMAMs for recombinant gene expression in mammalian is an ever expanding application of baculovirus vectors.  Her talk will encompass some of her research group’s recent work on the potential use of BacMams to transduce whole organs and

Expression Systems Media

Expression Systems Insect Cell Culture Media OET is pleased to offer a wide range of Expression Systems Insect cell culture media, from the very popular ESF 921, to specialized insect transfection media. Expression Systems’ media are easy to adapt your cells into and the insect specific media gives great protein yield, when compared to rival media. ESF 921 Insect Culture Media OET use ESF 921 for all in-house work, due

Bac to our Roots!

Ever wondered where the baculovirus insect cell expression system came from? The clue is in the name – of course it came from viruses that naturally infect insect caterpillars or larvae and can cause a nasty lytic disease.  The symptoms are quite dramatic! You may not realise it, but insects are prone to all manner of diseases caused by a variety of pathogens including: viruses, bacteria, fungi, microsporidia, nematodes and

Virus Like Particles VLPs for Therapeutics and Research

Oxford Expression Technologies (OET) is now able to apply its flashBAC baculovirus expression system to vaccine production, particularly in the exciting new field of virus like particle (VLP) vaccines. A virus like particle is an assembly of virus structural proteins that mimics the configuration of a real virus, except that it contains no genetic material. If a person is vaccinated with VLPs then an immune response is generated as if

“Global Success” Says Oxford Brookes University

A glowing impact case study by Oxford Brookes University highlights the benefits and hard work we have put into to developing a unique and advanced protein production system, labeling OET as a global success in the field of baculovirus research. Read below to find out more or click here to view the full article.   Oxford Expression Technologies Since the early 1990’s baculoviruses have been used for producing complex proteins

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