News & Press

Why the Insect Cell System is a Boost for Vaccine Development

In an article published by New Scientist this week as part of the Value of Vaccines campaign, Prof. Linda King, founder of Oxford Expression Technologies explains why the insect cell system has become a popular platform for vaccine development – particularly in the light of the Covid-19 pandemic. FULL ARTICLE

SARS-CoV-2 (COVID-19 Virus) Research

OET is currently helping COVID-19 research efforts by producing the recombinant spike glycoprotein of SARS-CoV-2 for clients. The protein will be used for further research, diagnostics and potential vaccine production. OET is also engaged in in-house COVID-19 research and is working on an insect cell-based vaccine using our flashBAC system enabled through funding from Innovate UK/Department of Health through the Vaccines for Global Epidemics:development and manufacture initiative

Message to Customers

At the present time Oxford Expression Technologies remains open and is working to complete client projects and dispatch kits and products. Our timescales may be slightly delayed whilst we comply with Government restrictions and prioritise the safety and wellbeing of OET staff. We will be contacting customers to ascertain that they are able to receive goods before shipping and are pleased to report that we can now ship media to

Introduction to the Baculovirus Expression System

Baculoviruses are in many respects an odd choice for use as an expression system to make recombinant proteins.  In their natural environment they infect insect larvae/caterpillars, which frequently results in the death of the host and its reduction to a puddle of progeny virus (Fig. 1).  They are also unusual in that they produce two structurally different forms in their life cycle. The first is a lipoprotein-enveloped particle that buds

Selecting a Protein Expression System

A major decision facing anyone starting a new project requiring any quantity of recombinant protein is selecting a protein expression system. A quick search online will unearth a large number of options and an often bewildering choice of different vectors to use within any given system. For the novice, this can be daunting! It may sound obvious, but the first thing to do is to decide what you want your

Expression Systems Media

Expression Systems Insect Cell Culture Media OET is pleased to offer a wide range of Expression Systems Insect cell culture media, from the very popular ESF 921, to specialized insect transfection media. Expression Systems’ media are easy to adapt your cells into and the insect specific media gives great protein yield, when compared to rival media. ESF 921 Insect Culture Media OET use ESF 921 for all in-house work, due

New pOET9 Vectors!

pOET9 transfer vectors from OET incoporate baculovirus technology with unique mammalian promoters to facilitate protein production in mammalian cell lines.

OET at the European Congress of Virology 2019

The OETeam have returned after a very successful four days at the European Congress of Virology 2019 hosted in Rotterdam, the Netherlands. As one of the congress sponsors, OET’s exhibition stand proved popular among both experienced and new baculovirus researchers as well as those individuals curious for an alternative protein expression platform.  In addition, four OET scientists were each able to present a research poster, all of which can be

Impact of Brexit

As you are aware the UK is due to leave the EU. Negotiations are still ongoing so it is yet unclear how this will affect trade going in and out of the UK. OET will be preparing for all possible outcomes as best we can to ensure that customer orders can still be fulfilled. However, we recommend that if you know you will require OET products in the initial months

OET Visits Key Partners in Mexico for Diabetes Type I Research

OET scientists, Dr Mine Aksular and Dr Leo Graves, recently travelled to Mexico City to spend six days visiting the Centre for Molecular and Cell-Based Therapeutics (CMCBT) as part of an international research collaboration (TRANSDIA) investigating a novel therapy for type I diabetes. Accompanied by collaborator Dr Stephen Hughes from the Nuffield Department of Surgical Sciences, Oxford University, the team were able to provide expert advice and practical guidance on

OET Presenting at South Wilts Virus Group Annual Meeting

OET will be sponsoring and presenting at this year’s South Wilts Virus Group (SWVG) annual meeting on Thursday 24th May. The event, hosted by Oxford Brookes University Department of Biological and Medical Sciences, will allow OET scientists to exhibit our current research achievements and network with other specialists in the virology field. The SWVG is a forum for virologists in the Wiltshire/Surrey/Berkshire/ Oxfordshire region. The organisation originally began in 1952

OET is Awarded £2 Million Vaccine Development Contract

Oxford, UK – 4th May 2018   Oxford Expression Technologies Ltd (OET) is pleased to announce that it has been awarded a £2M contract from Innovate UK as part of the ‘Vaccines for Global Epidemics’ Round 2 competition. The award will allow OET to continue its ongoing work in developing the first economically viable vaccine against Crimean Congo Haemorrhagic Fever (CCHF) virus. The Vaccines for Global Epidemics competition supports the

Product Launch – pOET8!

November marks the welcome of OET’s newest product – the pOET8 baculovirus transfer vectors (pOET8.VE1; pOET8.VE2; pOET8.VE3).  Compatible with any baculovirus expression system, including our own flashBACTM technology, the new range of pOET8 vectors are proven to help increase recombinant protein production in insect cells. The increased yield is achieved by allowing co-expression of foreign genes with a vankyrin expression cassette.  This gene cassette comprises the Campoletis sonorensis ichnovirus P-vank-1 protein

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