Baculoviruses are in many respects an odd choice for use as an expression system to make recombinant proteins.  In their natural...

A blog on baculovirus P10 structures and the role in insect cells might appear a slightly odd topic for a blog from a company based on...

A frequent customer query concerns baculovirus transfer vector plasmid compatibility with either flashBACTM or other systems for making...

A question we are asked from time to time is to identify baculovirus transfer vectors compatible with our flashBAC™ system. We obviously...

There are many methods available for the titration of recombinant baculoviruses.  One of the most convenient is the use of the...

One of the unexpected offshoots of the baculovirus expression system has been its development as a vehicle for the delivery of genes to...

Ever wondered where the baculovirus insect cell expression system came from? The clue is in the name – of course it came from viruses...

Have you ever wondered why the baculovirus we use for most protein expression purposes is called AcMNPV?  This is short for Autographa...

Using baculovirus expression vectors to produce virus-like particles (VLPs) is not new.  Intact, non-infectious poliovirus1 and...

A question that comes up repeatedly is the long term stability of recombinant budded baculovirus stocks.  This is a particular issue now...

Knowing the infectious titre of a recombinant virus stock is really important prior to testing for protein production in insect cells. ...

We were going to devote this blog to a comprehensive account of how you might determine the infectious titre of your virus stock. ...

In our last blog post we talked about the process of transfecting insect cells with virus DNA and how you could recognise success or...

Independent of the method you use to produce recombinant viruses, at some point you have to transfect insect cells with virus DNA to...

Ok, so the Bard is probably spinning in his grave at our blatant plagiarism of the script from the “Scottish Play” (it is bad luck to use...

The flashBAC™ system is a revolutionary platform technology for the production of recombinant baculoviruses in insect cells. It...

There are 2 main methods through which you can happily produce recombinant baculoviruses, firstly by using systems based on homologous...

As with all protein expression systems the baculovirus has its advantages and set-backs, the trade-off for high levels of expression,...

Thankfully baculoviruses don’t go through a rebellious teenage phase. They do however have a well-defined 2 step life cycle. Here we will...

A quick introduction into baculoviruses and baculovirus expression vectors, brought to you by OET. Short answer: An insect virus which...