Oxford Expression Technologies

Plant derived recombinant proteins & matching antibodies

Recombinant proteins are produced by transient expression using plant viral vectors in Nicotiana benthamiana. The matching antibodies are produced in various animals using the above recombinant proteins. This exclusive plant expression system confers our proteins with unique qualities: Animal-free plus Serum-free: Production in plants eliminates the risk of exposure to retroviruses and other agents that may be present in animal derived material. This makes our products ideal for animal and cell culture work. Complex proteins with post-translational modifications: Plants produce recombinant proteins in a very similar way to mammalian cell cultures, including disulfide bonds and other post-translational modifications. Functional: Plant produced recombinant proteins are active, unlike many obtained from bacteria. Even when glycosylation in plants is different from mammalian expression systems, our proteins are as active as their counterparts from CHO or similar. Endotoxin-free plus Antibiotic-free: Recombinant proteins produced in plants have lower endotoxin levels (<0.04EU/μg LAL Method) than proteins produced in bacterial systems .This is especially important in animal experiments avoiding pyrogenic and pro-inflammatory activity. High purity: Plant produced recombinant proteins are ≥97% pure.